CXCR2 and pancreatic neoplasm: In murine oral, renal, and pancreatic tumor models, CXCR2 inhibition results in neutrophil depletion coinciding with increased survival, T cell infiltration, and immunotherapy response (Chao et al., 2016; Najjar et al., 2017; Steele et al., 2016; Sun et al., 2019).