DSG2 and esophageal squamous cell carcinoma: In patients with ESCC in the training cohort, mean ± SD serum DSG2 concentration was 0.168 ± 0.135 ng/ml, while values in the early-stage disease and healthy control groups were 0.156 ± 0.123 and 0.093 ± 0.069 ng/ml, respectively (Table 2).