DSG2 and esophageal squamous cell carcinoma: Analysis of all patients with ESCC in the training cohort indicated that DSG2 had an AUC value of 0.724 (95% CI: 0.652–0.796) for distinguishing individuals with ESCC from healthy controls, with sensitivity/specificity of 38.1% (95% CI: 28.6–48.6%)/84.8% (95% CI: 75.4–91.1%) (Figure 4 and Table 3).