LRRK2 and Crohn disease: Because LRRK2 is linked to iPD, but also to other diseases of inflammation including Crohn's disease and mycobacterial infection, it could be that late systemic inflammation in worsening disease may manifest in increased LRRK2 activity and increased phosphorylated Rab10 (eg, responsive to aggregated α‐synuclein as we detected recently in monocytes).31