Nevertheless, a cohort of 201 consecutive Chinese patients with MTC (Shi et al. 2019) demonstrated that PD-L1 positivity was associated with more aggressive clinico-pathologic features, such as larger tumour size, number of lymph node metastases and advanced TNM staging and was independently predictive of morphological and/or biochemical recurrence or persistent disease (Sørlie et al. 2003). The gene discussed is CD274; the disease is neoplasm.