In addition, it is evident that other IFNs (including IFNγ and both isoforms of IFNλ) are also present within the islet milieu during the progression of type 1 diabetes and that, collectively, these (and other) cytokines determine the rate and extent of beta-cell loss (Huhn et al. 2008, Colli et al. 2020). Here, IFNG is linked to type 1 diabetes mellitus.