IFNA1 and enterovirus infectious disease: IFNα is induced in response to viral infection and there is now substantial evidence implicating the establishment of a persistent enteroviral infection in the β-cells during an early phase of the disease process (Alidjinou et al. 2014, Jean-Baptiste et al. 2017, Qaisar et al. 2018, Dunne et al. 2019, Akhbari et al. 2020, Marroqui et al. 2021).