ALB and cancer: Thus, these nanomaterials with extremely low systemic toxicity have been studied as a versatile platform for diagnosis and precision therapy.15–17 For example, Abraxane fabricated via hydrophobic interactions between HSA and paclitaxel, a paclitaxel albumin nanoparticle, has been approved by FDA for treating various cancers.18 Of note, HSA-α-Pc displayed a better ROS generation ability than that of HSA-β-Pc, and its highly efficient PDT/PTT dual-phototherapy was well evidenced via in vitro and vivo experiments under a single 808 nm laser irradiation (Scheme 1).