In vitro studies found that CEP55 overexpression induces uncontrolled cell proliferation via the PI3K/Akt signaling pathway.9 By contrast, CEP55 deregulation is associated with incomplete and abnormal cell division.10,11 The desired outcome of this anticancer strategy is that the inhibition of CEP55 activity results in aberrant cell division followed by cancer cell death. The gene discussed is CEP55; the disease is cancer.