TNS1 and chronic obstructive pulmonary disease: It has been proven that apoptosis of CMC (without signs of necrosis) is accompanied by an increase in the serum concentration of cardiospecific Tns. Thus, any physiological (physical activity, old age) and pathological (HF, AH, COPD, etc.) conditions that enhance apoptosis may be accompanied by the release of cardiospecific Tns from CMC and an increase in serum levels