In other pathological conditions that are accompanied by inhibition of the filtration rate, for example, in sepsis, serum levels of cardiospecific Tns are positively correlated with serum creatinine levels (Røsjø et al., 2011; Wilhelm et al., 2014), which also accumulate due to a decrease in the filtration capacity of nephrons. The gene discussed is TNS1; the disease is Sepsis.