Recent research suggests that cancer therapies, such as immunotherapy and radiotherapy, can induce ferroptosis partly through modulating SLC7A11 expression (Lang et al., 2019; Lei et al., 2020); knockout or inhibition of SLC7A11 has a significant inhibitory effect on lung cancer and pancreatic cancer cells (Ji et al., 2018; Sharbeen et al., 2021). The gene discussed is SLC7A11; the disease is familial pancreatic carcinoma.