TP53 and erythroplasia: Genetic alteration, like Polysomy of chromosomes 7 and 17 (Hittelman et al., 1993), LOH, or allelic gain at 9p, 3p, within the Rb, p53, or DCC gene region have been implicated in erythroplakia (Partridge et al., 1998; Mithani et al., 2007).