These results are also consistent with previous studies in which Bandyopadhyay et al. (2010); Sharma et al. (2013a) showed an increase in CXCR2 and/or TGF-β levels in aggressive breast cancer cells post treatment with doxorubicin, whereas the targeting of either of them was able to increase the response of cancer cells to doxorubicin. Here, TGFB1 is linked to breast cancer.