Initial symptoms: chest discomfort, fatigue, myalgias of lower limbs Other symptoms: chest pain, dyspnea, rash, diplopia or dysphagia, elevated troponin I, CK, CK-MB, NT-Pro BNP and myoglobin, cardiac arrest, hypotention, multisystem organ failure ECG: prolongation of the PR interval, RBBB, second degree of AV block, extensive ST-elevation ( lead I, AVL, AVR, V1–V5) ECHO: LVEF of 49%, thickened interventricular septum, gradual hypokinesis with LVEF down to 40% Cause of death: multisystem organ failure. The gene discussed is NPPB; the disease is cardiac arrest.