Future efforts should continue to explore the potential for PSMA in neuro-oncologic imaging, specifically focusing on proposed mechanism(s) of PSMA expression in CNS tumors, differential imaging performance by CNS tumor type, direct comparison of PSMA-targeted PET to other neuroimaging modalities for diagnosing and monitoring CNS tumors, and direct comparison of competing PSMA-binding radiotracers. The gene discussed is FOLH1; the disease is central nervous system neoplasm.