These results based on tumor purity, revealing a significant correlation between EpCAM expression, and B cell markers (CD19, CD79A), CD8+ T cells markers (CD8A, CD8B), CD4+ T cell markers (CD4), M1 macrophage markers (NOS2, IRF5, and PTGS2), M2 macrophage markers (VSIG4, MS4A4A), neutrophil markers (CEACAM8, ITGAM, and CCR7) and dendritic cell markers (HLA-DPB1, HLA-DQB1, HLA-DRA, HLA-DPA1, CD1C, NRP1, and ITGAX) in PCa. This evidence concerns the gene IRF5 and posterior cortical atrophy.