Immunoblotting against BAX and the activated (cleaved) form of the apoptotic executioner protein caspase-3 from A2780 ovarian cancer cells further verified the above results (Figures 6C–E), confirming that the inhibitory effect of cAMP on apoptosis of ovarian cancer cells is dependent on its ability to inhibit the apoptosis pathway. Here, CASP3 is linked to ovarian carcinoma.