BSG/CD147 has been implicated in tumor metastasis, inflammation and viral infection (Pushkarsky et al., 2001; Chen et al., 2005; Douglas et al., 2014; Zhang et al., 2018) and also previously shown to facilitate SARS-CoV invasion in host cells (Chen et al., 2005; Wang et al., 2020). The gene discussed is BSG; the disease is viral infectious disease.