On the other hand, BSG/CD147, which belongs to the Ig superfamily is expressed in several tissues like the brain, heart, liver, kidney etc and might play a complex role in COVID-19 and possibly contribute to the worse prognosis of patients with other co-morbidities (Radzikowska et al., 2020; Fenizia et al., 2021). Here, BSG is linked to COVID-19.