Indeed, in an effort to identify high confidence biomarkers for CRC, Jung Y et al. analyzed 91 CRC candidate biomarker genes and identified SAPCD2 as one of the 9 high confidence biomarkers for CRC diagnosis 22, further supporting the potential value of SAPCD2 a key biomarker for the detection of malignancy. This evidence concerns the gene SAPCD2 and colorectal carcinoma.