In contrast to healthy adult cells, expression of CD98hc is found in a wide variety of different cancer cells such as renal cell cancer 35, non-small-cell lung cancer 36, pulmonary neuroendocrine tumors 37, squamous cell carcinoma of the lung, thymic epithelial tumor 38, oropharyngeal squamous cell carcinoma 39, prostate cancer 40, gastric carcinoma 41 and cancer of the tongue 42. The gene discussed is SLC3A2; the disease is oropharynx squamous cell carcinoma.