None of the CCA tissue samples showed a strong BLVRB expression level, 8.7% (16/184) showed a moderate expression level, 84.2% (155/184) showed a weak expression level, and 7.1% (13/184) of samples were negative for BLVRB expression (Fig. 1C and 1D, P < 0.001). Here, BLVRB is linked to cholangiocarcinoma.