Our study showed that the upregulation of CAV2 or Wnt7A results in the downregulation of the expression of both endocytosis-related polar proteins, whereas the upregulation of MiR-4723 showed an opposite result, thus leading to the inference that the upregulation of CAV2 inhibits endocytosis to an extent, thereby affecting the MiR-4723/Wnt7A pathway and promoting the development of pancreatic cancer. This evidence concerns the gene WNT7A and pancreatic neoplasm.