CAV2 and familial pancreatic carcinoma: By qRT-PCR analysis, we found that CAV2 gene expression was highest in BXPC-3 and PANC-1 in various types of pancreatic cancer cells (e.g., Fig. 1E, P < 0.05).We also explored the CAV2 protein expression in human pancreatic cells HPC-Y5 with PANC-1 and BXPC-3 and found that the protein expression was significantly down-regulated in HPC-Y5 (e.g., Fig. 1F, P < 0.05).