Based on a combination of univariate Cox regression and least absolute shrinkage and selection operator (LASSO) regression, a prognostic model including 5 glucometabolic genes (AHCY, GALNT3, AKR1C2, NCAN and FBP2) was established and proven to be effective in predicting NB patient prognosis in different cohorts. The gene discussed is NCAN; the disease is neuroblastoma.