To determine whether miR-873 down-regulation is involved in WZY-321-induced XAF1 expression in glioma cells, the cultured glioma cells were divided into 3 groups of (1) NC mimic, (2) NC mimic + WZY-321, (3) miR-873 mimic + WZY-321. The gene discussed is XAF1; the disease is central nervous system cancer.