Up to now, besides PML-RARα fusion gene, there are at least 13 RARα fusion genes involved in the pathogenesis of APL, which includes PLZF-RARα, NPM-RARα, NuMA-RARα, STAT5b-RARα, PRKAR1A-RARα, FIP1L1-RARα, BCoR-RARα, OBFC2A-RARα, TBLR1-RARα, GTF2I-RARα, IRF2BP2-RARα, FNDC3B-RARα, STAT3-RARα 13-16. The gene discussed is RARA; the disease is acute promyelocytic leukemia.