Mutations on VCP have been linked to several forms of neurodegenerative disorders (Watts et al., 2004; Johnson et al., 2010; Meyer and Weihl, 2014; reviewed in Sun and Qiu, 2020) and endogenous VCP associates with protein inclusions in both Huntington’s disease and Lewy body dementia (Hirabayashi et al., 2001). The gene discussed is VCP; the disease is juvenile Huntington disease.