In regards to orthostatic hypotension, carriers of the VDR rs739837 GG genotype had increased odds (OR = 2.23; 95% CI = 1.05–4.70; p = 0.036) for development of this AE, whereas carriers of the VDR rs731236 TC (OR = 0.52; 95% CI = 0.29–0.93; p = 0.026) and CC genotype (OR = 0.38; 95% CI = 0.16–0.91; p = 0.029), as well as carriers of at least one VDR rs731236 C allele (OR = 0.48; 95% CI = 0.28–0.84; p = 0.010) had decreased odds for development of orthostatic hypotension. This evidence concerns the gene VDR and hypotensive disorder.