2001) for mild and moderate AD.4,12,13 Rivastigmine (Exelon) 3 (approved by FDA in 21 April 2000) is also useful for mild and moderate dementia patients caused by AD or Parkinson's disease.4,14,15 Donepezil (Aricept) 4 is also a cholinesterase inhibitor approved by FDA on 25 Nov. Here, BCHE is linked to Alzheimer disease.