CYP1B1 and obesity due to melanocortin 4 receptor deficiency: It is a well-known fact that nutrition confers protection against numerous types of chronic diseases such as obesity, diabetes, cardiovascular diseases, osteoporosis and bone fractures, cancer and dental diseases.76 In the last decade various nutrients have been recognized to aid in the control and prevention of these diseases by affecting the activities of CYP1B1 (Table 1).