Their results concluded that the CYP1B1 gene is a major gene for PCG al (GLC3A) although a different pattern of CYPB1 mutations and benign sequence variants were found in Indonesian patients compared with European (white) patients.43 Similarly, Mukesh and coworkers evaluated the mutation profile of CYP1B1 in 50 North Indian primary congenital glaucoma (PCG) patients. This evidence concerns the gene CYP1B1 and primary congenital glaucoma.