As compared to the controls, the patients from Russian ethnic group exhibited differences in genotype distributions in CYP1B1 rs1056836 site.52 In the same year Majid and research group also conducted a similar study in Iran aiming to investigate CYP1B1 L432V polymorphism by selecting 65 lung cancer patients and 80 healthy controls.53 Mitsui et al., determined the expression of CYP1B1 in renal cell carcinoma (RCC) cell lines, tissue microarrays of 96 RCC and 25 normal tissues. The gene discussed is CYP1B1; the disease is hereditary clear cell renal cell carcinoma.