Cancer susceptibility candidate 2 (CASC2), a long non-coding RNA (lncRNA) downregulated in HCC cell lines, can inhibit tumorigenesis by means of functioning as a competing endogenous RNA (ceRNA) for miR-367 and weakening its pro-metastatic effects through targeting FBXW7 (106). Here, FBXW7 is linked to hepatocellular carcinoma.