Compared to the other five tumor markers, higher diagnostic accuracy of CEA was shown in PE (AUC, 0.890; sensitivity, 74.1%; specificity, 95.5%), serum (AUC, 0.834; sensitivity, 64.4%; specificity, 92.2%), and PE/S (AUC, 0.811; sensitivity, 63.7%; specificity, 94.5%). This evidence concerns the gene CEACAM5 and neoplasm.