Moreover, myeloid cells also expressed high levels of arginine (ARG) that binds to intercellular adhesion molecule 1 (ICAM1) in follicular cells, whose expression levels have been shown to be increased in PTC, poorly differentiated thyroid cancer (PDTC), and anaplastic thyroid cancer (ATC) and which has been proven to be an effective therapeutic target in advanced thyroid cancer (55, 56). This evidence concerns the gene ICAM1 and thyroid gland undifferentiated (anaplastic) carcinoma.