We then infected BCP-ALL cells with PPTC7 overexpression lentivirus, and found that PPTC7 overexpression strongly promotes the mitochondrial energy metabolism, including promote the production of CoQ10 and ATP, inhibit the production of ROS (Figures 5B–E), which demonstrated that PPTC7 positively regulate mitochondrial energy metabolism through COQ10 in BCP-ALL cells. This evidence concerns the gene PPTC7 and acute lymphoblastic leukemia.