The cytotoxicity assay showed that, compared with the control group, the expression of CD107a and GZMB was significantly reduced in NK cells co-cultured with miR-582-overexpressing BCP-ALL (NALM-6, KOPN-8, as well as SUP-B15) cells (Figures 6D, E;Supplementary Figures S4B, C). This evidence concerns the gene LAMP1 and acute lymphoblastic leukemia.