To narrow down the responsible cell type and to rule out any contribution of potentially targeted T or B cells (6, 21) in the CD11c-cre deleter strain, we generated DCs from bone marrow using either Flt3L (FL-DCs), which is necessary for systemic and intestinal conventional DC (cDC) development (2) or GM-CSF/IL-4 (G4-DCs) and adoptively transferred these into C57BL/6J recipients 3 days prior to colitis induction with DSS. The gene discussed is ITGAX; the disease is colitis.