Since a positive correlation between circulating anti-Hsp90 IgG and IFN-ɣ has been previously also found in patients with rheumatoid arthritis (4), it is likely that anti-Hsp autoantibodies are involved in the development of some autoimmune diseases in an IFN-ɣ-associated manner. Here, HSP90B2P is linked to rheumatoid arthritis.