CD8A and neoplasm: Accumulation of Treg cells in tumor-draining lymph nodes (TDLN) was also inhibited in Foxp3CreNr4a-DcKO mice, and the fractions of CD8+ T cells and proliferating CD8+ T cells were significantly increased in the TDLN of Foxp3CreNr4a-DcKO mice when compared to the wild-type.