SNPs associated with the ESR1 gene and GREB1, an early response gene that is regulated by oestrogens as well as androgens in hormone-dependent cancers (Cheng et al. 2018), were reported in endometriosis GWAS including large-scale meta-analysis (Rahmioglu et al. 2014, Sapkota et al. 2017), although not all studies have replicated findings of an association with the rs11674184 SNP of the GREB1gene (Matalliotaki et al. 2019). This evidence concerns the gene ESR1 and endometriosis.