In a small study Wang et al. focused on endometriomas in Han Chinese women finding the most significant signalling pathway was that associated with IGF1 receptor (Wang et al. 2017) which is interesting as macrophage-derived IGF1 has recently been highlighted as a nerve sensing factor in endometriosis-associated pain (Forster et al. 2019). The gene discussed is IGF1; the disease is endometriosis.