GREB1 and endometriosis: SNPs associated with the ESR1 gene and GREB1, an early response gene that is regulated by oestrogens as well as androgens in hormone-dependent cancers (Cheng et al. 2018), were reported in endometriosis GWAS including large-scale meta-analysis (Rahmioglu et al. 2014, Sapkota et al. 2017), although not all studies have replicated findings of an association with the rs11674184 SNP of the GREB1gene (Matalliotaki et al. 2019).