OGT and cancer: O‐GlcNAc is a common modification that regulates the stability, trafficking, and function of many proteins and OGT, the sole enzyme known to catalyze O‐GlcNAcylation, is indispensable for the proliferation of all 975 cancer cell lines in the DepMap database (Hart et al, 2007; Meyers et al, 2017).