To investigate the downstream target genes regulated by MAEL and the mechanism underlying its promotion of EOC cell invasion and EOC metastasis, we examined the mRNA expression profiles in ES2-shControl and ES2-shMAEL-1 cells using a Human Tumor Metastasis RT2 ProfilerTM PCR Array (Super Array Bioscience, America) containing 84 cell metastasis-related genes. This evidence concerns the gene MAEL and neoplasm.