In LUSC and ESCA, TUBA1C expression was negatively related to the expression of most immune checkpoints, while in OV, LGG, BRCA and BLCA, a positive association of TUBA1C expression with immune checkpoints was revealed (Fig. 11A), suggesting that TUBA1C has promise as a predictive factor for immunotherapeutic response in patients with these cancers. Here, TUBA1C is linked to cancer.