MAPT and tauopathy: Although the majority of tauopathies are sporadic, more than 50 mutations in the exons and introns of the MAPT gene have been reported to be linked to the onset of tauopathies, and these cases are referred to as frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17T) [103, 143, 235, 275].