We confirmed that CALB1+/TMEM200A+ DA cells were selectively enriched in PD (Fig. 3e; Wilcoxon rank-sum test P < 0.05), as were CALB1+/TMEM200A− DA cells, although the log fold change difference was lower (Fig. 3e; log2(fold change 1.13) for the TMEM200A− group versus log2(fold change 1.32) for the TMEM200A+ group; Supplementary Table 5). This evidence concerns the gene TMEM200A and Parkinson disease.