DLGAP3 and epilepsy: As shown in the western blots, SAPAP3 was upregulated in the mouse model of pilocarpine-induced epilepsy (cortex: epilepsy group, 1.32 ± 0.23 vs. the control group, 0.58 ± 0.03; p < 0.01; hippocampus: epilepsy group, 2.04 ± 0.12 vs. the control group, 0.69 ± 0.15; p < 0.001; Fig. 2B).