The hippocampus is considered the core source of epilepsy, and because hippocampal tissues cannot be obtained from patients and controls, we tested the expression patterns of SAPAP3 in the hippocampus and cortex of a mouse model of pilocarpine-induced epilepsy to confirm the expression of SAPAP3 in patients and to exclude the possible effect of AEDs. Here, DLGAP3 is linked to epilepsy.