STC2 and colorectal cancer: Moreover, it was discovered that the expression of STC2 changed overtly in solid cancers such as colorectal cancer [25], nasopharyngeal carcinoma [26], endometrial carcinoma [27], gastric carcinoma [28], hepatocellular carcinoma [29], head and neck squamous cell carcinoma [30], which indicated that STC2 took effect in cancer development and progression, including promoting cancer cells invasion and metastasis, suppressing the cells apoptosis and so on.