Moreover, it was discovered that the expression of STC2 changed overtly in solid cancers such as colorectal cancer [25], nasopharyngeal carcinoma [26], endometrial carcinoma [27], gastric carcinoma [28], hepatocellular carcinoma [29], head and neck squamous cell carcinoma [30], which indicated that STC2 took effect in cancer development and progression, including promoting cancer cells invasion and metastasis, suppressing the cells apoptosis and so on. Here, STC2 is linked to cancer.