We additionally validated the functional effects of two other SNPs—rs17293632 near SMAD3 (linked to AS, CR, MS, PS, RA and UC), and rs6784841 near LMOD3/FRMD4B genes (linked to CD) (Figure 8D; Supplementary Figure S9B, S10B). The gene discussed is FRMD4B; the disease is myeloid sarcoma.