Poorly differentiated lung adenocarcinoma cells were detected in GR-CDXL1, GR-CDXL2 (Supplemental Figure 2C), and GR-CDXL4 (Figure 1C) tumors by HES stain, while in patient L3, TB 10% of tumor cells were positive for p40 and CK5/6 squamous markers (Supplemental Figure 2C). This evidence concerns the gene RRBP1 and neoplasm.