Univariate Cox regression showed that OS was associated with MELK expression (MELK high vs. low, HR = 2.308; 95% CI 1.029,5.167; p < 0.001), age (> 60 vs. ≤ 60, HR = 2.629; 95% CI 1.398,4.943, p = 0.003), vascular invasion (vascular invasion-positive vs. negative, HR = 1.939; 95% CI 0.992,3.789, p = 0.053), and tumor status (tumor-free vs. with tumor, HR 2.992; 95% CI 1.557–5.749, p = 0.001). The gene discussed is MELK; the disease is neoplasm.