Its overexpression or variance may contribute to the development of tumors.2,3,4 Epidermal growth factor receptor is reported to be overexpressed in various solid tumors, including squamous cell carcinomas of the head and neck (SCCHN), nasopharyngeal carcinoma (NPC), and colorectal cancer (CRC).5,6,7. The gene discussed is EGFR; the disease is colorectal carcinoma.