CD8A and viral infectious disease: More specifically, our aims were to: (i) characterize microbleeds as an neuroimaging marker starting at early stages of CNS viral infection by T2*-weighted MRI; (ii) determine whether VSV-induced cerebrovascular damage was caused by the virus or infiltrating immune cells; (iii) evaluate whether adoptively transferred virus-specific CD8 T cells could prevent cerebrovascular damage; (iv) develop an MRI technique to label and track antiviral CD8 T cells; (v) define the relationship between microbleeds and CD8 T cells.