CXCL12 and acute kidney injury: Finally, to clarify the miR-103a-3p-dependent CXCL12 functional regulation in AKI, a CXCL12 overexpression plasmid was transfected in HK-2, and HEK293 cells were transfected with LPS+miR-103a-3p mimics, LPS+miR-103a-3p mimics/CXCL12 or LPS.