We did not find a significant difference in adiponectin values in patients with CHB on antiviral therapy according to the different degree of liver fibrosis, based on the results of FIB-4 and APRI score, although some discrepancies were observed in the ratio of serum adiponectin levels to higher degrees of liver fibrosis assessed based on these scores. The gene discussed is ADIPOQ; the disease is Hepatic fibrosis.