All the factors, including age, diabetes mellitus, sST2 level, NT-proBNP, CK-MB, cTNI, NLR, fasting blood sugar, preoperative blood pressure, and intraoperative hypotension, showing a statistically significant difference between the two groups underwent univariate regression analysis, and the results revealed that sST2 level, CK-MB, cTNI, NLR, SBP, DBP, and intraoperative hypotension were related to CSF/NRF. The gene discussed is NPPB; the disease is diabetes mellitus.